Abstracto

Study of the effect of nutrition interventions on the recovery of fatigue: a placebo-controlled, randomized, double-blinded cross-over trial

Bo Yang, Jian Zhang, Hua Zhao, Yukang Cao, Qing Wu

Objectives: To investigate the effects of multivital supplement on physical overtraining young males who were on ordinary Chinese diet, and the suitable time of using mulvital on young males to dispel fatigue.

Methods: 240 young male volunteers after thousand meters running were randomly divided into group A (mulvital was first given, then placebo) and group B (placebo was first given, then mulvital). Medical history, physical examination, the Fatigue Assessment Scale, as well as hormone axises and cellular immune parameters were evaluated after high-intensity training program.

Results: The recovery of pituitary-adrenal axis and immune system of the mulvital group were significantly better than the placebo group (P<0.05). There was no significant difference of the pituitarygonadal axis and fatigue scale score between two groups were observed. The pituitary-thyroid axis and symptom check list score of the medication group were significantly better than the placebo group after the intervention using the mulvital (P<0.05).

Conclusions: Our research confirmed that the use of mulvital is beneficial for the recovery of pituitaryadrenal function, pituitary thyroid function, immune function, and psychological status. The earlier application of mulvital is better for the recovery.