Archivos de Biotecnología Industrial


Nucleic acid testing applications in molecular diagnostics.

Robert Davis

In order to create diagnostic applications for the cutting-edge method polymerase chain reaction, Roche and Cetus engaged into an agreement in 1989. Genes and pathogen genomes have been utilised to diagnosis disease since a new field of molecular diagnostics emerged. Automated laboratory platforms were developed to expedite the procedure and enable accurate and precise processing of patient blood samples. The use of nucleic acids in molecular diagnostics and its application to significant human diseases will be discussed in this chapter. Examples of nucleic acid markers that have had a significant clinical influence on healthcare are reviewed.