Investigación biomédica

Abstracto

Investigation of serum 25 hydroxy vitamin D level in critically ill children and its relation with demographic and clinical risk factors

Bahare Yaghmaie, Fatemeh Sayarifard, Mohammadreza Modarresi, Masoud Mohammadpour, Meysam Sharifzade, Abbas Hassani, Abbas Rahimi Foroushani, Parisa Khalili, Bahar Allahverdi

Background: Vitamin D is a pleiotropic hormone important for the proper functioning of multiple organ systems. It has been hypothesized that vitamin D deficiency could contribute to mortality, disorders, or worsen outcomes in critical illness. The aim of this study was to investigate the relation of vitamin D deficiency with potential demographic and clinical factors.

Methods: Eighty two children hospitalized in ICU section of Children’s Medical Center were contributed into this study and serum level of vitamin D was extracted from patients’ file.

Results: The level of vitamin D significantly decreased from 37.9532 to 23.8771 ng/mL. Logistic regression analysis, also, confirmed the relation between age and vitamin D serum level. This change probably was because of higher growth rate among children older than 2 years. So, vitamin D should be added to the older children’s nourishment.