Abstracto

Impact of electromagnetic irradiation produced by 3G mobile phone on brain neurotransmitters in mice during growth and development period

Fengming Li, Jin Chang, Yinggang Lv, Dianguo Xu, Jianhua Chen, Xuewen Sun

The aims of this study were to detect the levels of brain neurotransmitters in mice exposed to electromagnetic irradiation produced by 3G mobile phone (3G-EMI). The mice in the growth and development period were randomly divided into three groups: the control group (C), the low-radiation group (L), and the high-radiation group (H). Group L was irradiated 30 min × 3 times per day, and group H was irradiated 60 min × 3 times per day. The contents of Acetylcholine (Ach), Dopamine (DA), and serotonin (5-HT) in the brain were then detected by liquid chromatograph-mass spectrometer (LCMS/ MS). The contents of ach in the brain neurotransmitters of experimental groups were different, but the differences were not significant (P>0.05). The content of DA in brain of high radiation group (29.170 ± 2.469 ng/g) was significantly lower than that of low radiation group (34.487 ± 2.652 ng/g) (P<0.05). The Ach contents in all the experimental groups varied, but the differences were not statistical (P>0.05). The DA content in the high-radiation group (29.170 ± 2.469 ng/g) was statistically lower than the lowradiation group (34.487 ± 2.652 ng/g) (P<0.05). The content of 5-HT in group L (1.6648 ± 0.8136 ng/g) was statistically lower than group C (3.4518 ± 0.9930 ng/g) (P<0.05), while the content of 5-HT in group H (3.9240 ± 1.2523 ng/g) was statistically higher than group L (1.6648 ± 0.8136 ng/g) (P<0.05). 3G-EMI has certain impact on the contents of brain neurotransmitters during growth and development period.