Abstracto

Healthy human lung epithelial cells beas-2b cells exhibit pro-inflammatory reactions.

Seval Akpinar

An immune response to infection that involves both the innate and adaptive immune systems is called inflammation. If inflammation is allowed to persist unchecked, however, it can lead to a number of pathologies. Antioxidant-rich natural molecules have the ability to target the main causes of inflammation and have positive effects on health. In order to show the enhanced antioxidant and anti-inflammatory properties of the combination, human normal bronchial (Beas-2B) and prostate (HPrEpiC) epithelial cell lines were exposed to infectious stimulation and treated with phycocyanin (PC) and palmitoylethanolamide (PEA). The treatment significantly reduced the production of radical oxygen species (ROS), several inflammatory cytokines, and protected against cytotoxicity. By modifying three key factors, oxidative stress and inflammation were reduced.