Abstracto

Genetic effect of rs2248359 and rs2248137 CYP24A1 with serum level of CYP24A1 enzyme and 25-OHvitD3 on multiple sclerosis disease.

Shemaa A Soud, Salwa HN Al-Rubae'i

Our study attempted to clarify the genetic association between rs2248359 and rs2248137 CYP24A1 polymorphism and risk of MS in Iraq, and to explore their possible interactions with CYP24A1 enzyme and 25-hydroxyvitamin D3 (25-OHvitD3) serum level; as well as, with certain features in terms of age at onset, gender, disease duration, Expanded Disability Status Scale (EDSS) and disease lines.