Abstracto

Development of strategies for battle against COVID-19.

Iskra V Sainova

 Statement of the Problem: Despite of the key importance the immunity, the activated immune reaction, including by vaccines, could cause unwished effects, for instance in cases as allergies, auto-immune diseases and disorders, as well as cardio-vascular pathologies. Toxic side effects of the chemical anti-viral preparations should also be taken in consideration. So, the main goal is connected with suppression of the cellular penetration and/or replication of COVID-19, both in vitro and in vivo, by RNA-interference of respective viral genes with appropriate siRNAs.