Abstracto

Advances in diagnosis and treatment of breast cancer recurrence.

Maryam Manzoor1, Nishita Rastogi1, Shazia Rashid1*, Saraswat Basu2

Breast cancer is one of the leading causes of cancer-related deaths in women across the world which is mainly due to its ability to metastasize and pose a high risk of recurrence after treatment. In this review, some of the key factors that lead to breast cancer have been summarized and a more in-depth analysis of the factors involved in its recurrence has been explored. The different metabolic pathways and the role of genetic and epigenetic mechanisms that account for such aberrant processes have also been discussed. New therapies and drugs that have shown good efficacy against recurrent breast disease have been highlighted and an insight into new treatment modalities currently available has been provided. Also, new therapeutic approaches to treat recurrence in breast disease have also been explored.