Abstracto

Activation of neutrophils as potential therapeutic targets for cancer treatment.

Md Abdus Subhan

Neutrophils are essential for host protection against microbial infections and can be used as a mode of cancer therapy. They play dual role in cancer either as tumor promoting or antitumor. Neutrophil cytotoxicity is deceptive at the time of metastatic seeding and possibly at early stages of tumorigenesis but not in the microenvironment of a matured tumor. Application of neutrophils and their membranes for improved drug delivery and novel therapeutics as already attained inspiring results in preclinical settings.